Carfentanil, a synthetic opioid reported to be 100 times more potent than fentanyl, has been linked to an increase in drug overdoses in Colorado Springs. According to the Colorado Springs Police Department (CSPD), as of November 12, 2025, there have been 61 fatal drug overdose cases in the city this year. Fentanyl or carfentanil contributed to 29 of these deaths.
Law enforcement agencies have seized over 700,000 fentanyl pills in Colorado Springs during 2025. Of these, nearly 28,000 pills since September contained carfentanil. The CSPD’s Metro Division – Narcotics Unit and the Colorado Springs Resident Office of the Drug Enforcement Administration are leading these efforts as part of ongoing investigations.
Many of the seized substances appeared as “M30” tablets that look similar to legitimate prescription medications. Carfentanil has also been found in powdered form. Law enforcement reports that recent seizures often include mixtures containing both fentanyl and carfentanil. The appearance or color of these pills does not indicate their chemical makeup; laboratory testing is required for accurate identification.
The presence of carfentanil poses increased risks due to its high potency and potential dangers from accidental exposure. Naloxone (Narcan), an emergency antidote for opioid overdoses, may not be effective against carfentanil at standard doses; multiple high doses could be needed if exposure occurs.
Officials advise residents not to handle suspected fentanyl or carfentanil products and instead contact law enforcement immediately. The CSPD can be reached at 719-444-7000 for information regarding narcotics activity. Anonymous tips can be submitted through Pikes Peak Area Crime Stoppers at 719-634-STOP(7867) or online at Submit A Tip – Pikes Peak Crime Stoppers.
For additional information on synthetic opioids and public safety resources, visit the Drug Enforcement Administration’s website at https://www.dea.gov/ and its Fentanyl Free America campaign page at https://www.dea.gov/fentanylawareness.
“Carfentanil: A Synthetic Opioid Unlike Any Other
Colorado Springs Police Department | City of Colorado Springs”
